BIMU 8
CAS No. 134296-40-5
BIMU 8 ( —— )
Catalog No. M27487 CAS No. 134296-40-5
BIMU 8 is a selective agonist of 5-HT4 with EC50s of 18 nM, 77 nM, and 540 nM for wild-type 5HT4 receptor, T3.36A, and W6.48A mutant 5-HT4.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 163 | Get Quote |
|
10MG | 236 | Get Quote |
|
25MG | 394 | Get Quote |
|
50MG | 582 | Get Quote |
|
100MG | 827 | Get Quote |
|
500MG | 1674 | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
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Product NameBIMU 8
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NoteResearch use only, not for human use.
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Brief DescriptionBIMU 8 is a selective agonist of 5-HT4 with EC50s of 18 nM, 77 nM, and 540 nM for wild-type 5HT4 receptor, T3.36A, and W6.48A mutant 5-HT4.
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DescriptionBIMU 8 is a selective agonist of 5-HT4 with EC50s of 18 nM, 77 nM, and 540 nM for wild-type 5HT4 receptor, T3.36A, and W6.48A mutant 5-HT4.(In Vitro):BIMU 8 (0.003-0.1 μM) increases excitatory postsynaptic potentials amplitude without changing the membrane potential of any neuron in myenteric neurons of guinea pig ileum.(In Vivo):BIMU 8 (20-30 mg/kg s.c. and 60 mg/kg p.o. in mice; 20 mg/kg i.p. in rats), produces significant antinociception. In mice, BIMU 8 (10 μg; i.c.v) which is largely ineffective by parenteral routes induces antinociception.
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Synonyms——
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PathwayEndocrinology/Hormones
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Target5-HT Receptor
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number134296-40-5
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Formula Weight378.9
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Molecular FormulaC19H27ClN4O2
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Purity>98% (HPLC)
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Solubility——
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SMILESC(N[C@H]1C[C@@H]2N(C)[C@H](C1)CC2)(=O)N3C=4C(N(C(C)C)C3=O)=CC=CC4.Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Jian-Fa Zong, et al. [Studies on Alkaloid Constituents of Fritillaria Yuminensis]. Zhongguo Zhong Yao Za Zhi. 2019 Feb;44(3):495-499.
molnova catalog
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